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A new combination of bortezomib (Velcade) and two other drugs is showing a very high response rate in patients newly diagnosed with multiple myeloma, a team headed by Dana-Farber Cancer Institute investigators reported at the annual meeting of the American Society of Hematology.
The three-pronged regimen of Velcade, lenalidomide (Revlimid) and dexamethasone - referred to as [...]

Sickle cell disease (SCD) is an inherited blood disorder caused by a genetic mutation that leads to the generation of a mutant form of the beta-globin chain of hemoglobin (Hb). Red blood cells containing Hb with this mutant beta-globin chain change shape upon deoxygenation and this causes them to get stuck in blood vessels, depriving [...]

Pharmion Corporation (NASDAQ: PHRM) reported that data from 36 abstracts of studies investigating the company’s marketed and pipeline hematology products will be presented at the American Society of Hematology’s (ASH) 49th Annual Meeting and Exposition in Atlanta (December 8-11, 2007). These abstracts include summaries of data from studies of several key products in the company’s [...]

The American Society of Hematology (ASH), the world’s largest professional society of blood specialists, is honoring three scientists who have made notable contributions to the genetic understanding of disease. Carlo Croce, MD, will receive the Henry M. Stratton Medal, intended to honor an individual with a distinguished career in hematology, and William P. Vainchenker, MD, [...]

“Jehovah’s Witness patients no longer have to die for want of blood,” says Patricia Ford, MD, a hematologist/oncologist and Medical Director of the Center for Bloodless Medicine and Surgery at Pennsylvania Hospital, part of the PENN Medicine hospital network. Dr. Ford is one of the pioneers of bloodless surgery and has been teaching its technique [...]

Women die and get infections more often than men after heart surgery because they tend to receive more blood transfusions, which boost the risks of bad outcomes, according to a study published in the December Journal of Women’s Health.
Co-authored by researchers from the University of Rochester Medical Center and University of Michigan Health System, the [...]

No other stem cell is more thoroughly understood than the blood, or hematopoietic, stem cell. These occasional and rare cells, scattered sparingly throughout the marrow and capable of replenishing an entire blood system, have been the driving force behind successful bone marrow transplants for decades. Scientists, for the most part, have seen this as the [...]

There are estimated to be between 50,000 — 100,000 individuals in the U.S. diagnosed with chronic Immune Thrombocytopenic Purpura (ITP), an autoimmune disease that dramatically reduces the number of platelets in their blood — causing bruises, nosebleeds and, sometimes, life-threatening brain hemorrhages. Now, the results of an international multicenter clinical research study led by NewYork-Presbyterian [...]

LEO Pharma launches a new, safe drug, ATryn®, for preventing blood clots in patients. It concerns patients who, due to a genetic defect, cannot produce enough of the protein antithrombin III or whose antithrombin III is not sufficiently efficient. Antithrombin is a protein that is a key part of managing the coagulation process in the [...]

Bristol scientists have found that red blood cell transfusions given to people having heart surgery could increase the risk of heart attack or stroke.
Published in the latest issue [November 27] of the journal Circulation, the study looked at the association between red blood cell transfusion and adverse outcomes in over 8,500 cardiac surgery patients over [...]