Breast Cancer Patients Could Receive Wrong Treatment Because Of Errors In Widely Used Lab Tests

The Wall Street Journal on Friday examined the efficacy of two diagnostic tests used to determine which drugs to prescribe women with invasive breast cancer. According to the Journal, thousands of women with breast cancer might be receiving the wrong treatment because of errors in the two tests predominantly used to determine which drugs to [...]

Inaccurate Lab Tests Might Lead To Inappropriate Treatment Of Breast Cancer

Thousands of breast cancer patients might receive improper medications as a result of inaccurate results for two laboratory tests used to determine the most effective treatments for specific patients, the Wall Street Journal reports. According to the Journal, pharmaceutical companies are “trying to develop more medicines tailored to the individual characteristics of patients and their [...]

Targeted Digital Mammography May Be Cost-Effective Method Of Screening For Breast Cancer, But Digital Mammography For All Women Is Not

A cost-effectiveness study of the value of digital mammography breast cancer screening has found that digital mammography screening does not result in sufficient health gains to warrant its increased cost unless its use is limited to younger women or to women with dense breasts (Article, p. 1).
This article appears in Annals of Internal Medicine.
The study [...]

Breast Cancer Cells Have To Learn To Walk Before They Can Run

Early-stage breast cancer that has not yet invaded the surrounding tissues may already contain highly motile cells, bringing the tumor one step closer to metastasis, report researchers at the Salk Institute for Biological Studies.
Their study, published in the Dec. 30 issue of the Journal of Cell Biology, suggests that these cells, although not yet invasive, [...]

Taxol With Avastin Produces Noteworthy Results, Indiana University Breast Cancer Researcher Reports In NEJM

The positive results of the first nationwide clinical study showing the benefits of an antiangiogenic agent in breast cancer therapy are reported in the Dec. 27 issue of the New England Journal of Medicine.
The study with Avastin showed the biggest improvement in metastatic breast cancer ever reported in a chemotherapy-based clinical trial. It nearly doubled [...]

Cone Beam CT Faster, Potentially More Accurate Than Conventional Mammography

Cone-beam breast CT provides exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose to conventional 2D mammography, according to a new study by a team of researchers from the University of Texas M. D. Anderson Cancer Center in Houston.
Cone-beam breast CT employs a large area x-ray beam in conjunction with a [...]

Novel Method Used To Classify New Vs. Recurrent Cancer

Researchers developed a new method for distinguishing between breast cancer recurrences and new primary tumors.
One commonly used method is to detect changes in DNA copy number. Another is to compare clinical and pathologic characteristics of the two tumors.
Marc Bollet, M.D., of the Institut Curie in Paris and colleagues compared these two methods with a new [...]

GlaxoSmithKline Receives Positive EMEA Opinion For A Conditional Approval Of Tyverb®

GlaxoSmithKline (GSK) announced that Tyverb® (lapatinib) has received a positive opinion recommending a conditional marketing authorisation from the European Medicines Agency (EMEA). Lapatinib, in combination with capecitabine, is indicated for the treatment of patients with advanced or metastatic breast cancer whose tumours over-express ErbB2 (HER2). Patients should have progressive disease following prior therapy which must [...]

Chemotherapy And Tamoxifen Independently Reduce Risk Of Second Breast Cancer

Among breast cancer patients, both chemotherapy and tamoxifen independently reduced the risk of developing a second cancer in the other breast, according to a study published online December 25 in the Journal of the National Cancer Institute. The risk reduction persisted for at least 10 and 5 years, respectively.
For breast cancer patients the risk of [...]

Ireland Cancer Center Researcher Finds Standard Treatment For Breast Cancer Not Followed

Research out of the Ireland Cancer Center of University Hospitals Case Medical Center, in collaboration with six integrated health plans that are part of the Cancer Research Network, found that the majority of older women with early stage breast cancer fail to adhere to the standard of treatment - five years of daily oral use [...]