allcancercure.com

A novel compound in development by AstraZeneca as an oral tablet for hormone resistant prostate cancer (HRPC), ZD4054, could improve overall survival (OS) in men with metastatic HRPC, according to Phase II data published today in European Urology.[1]
Men with advanced prostate cancer may receive initially effective treatment with hormonal therapies to which the majority of [...]

US scientists reviewing 20 years of research and expert opinion on generic versus brand name drugs in the treatment of cardiovascular diseases found no clinical evidence showing brand names were superior to generic versions even though a substantial number of experts writing editorials advised against interchanging them.
The study was the work of Dr Aaron S [...]

Thirteen of the 20 cities in which a clinical trial was conducted for an artificial blood substitute had minority populations greater than that of the nation as a whole, according to records obtained by the Detroit Free Press.
The blood substitute Polyheme, manufactured by Northfield Laboratories, is made by extracting hemoglobin from human red blood cells. [...]

Early clinical trials “tend to enroll relatively healthy white males but few children, women, minorities and older patients” — a disparity that can result in research that “ignores biological differences that cause people of varying ages, genders and ethnicities to react differently to therapies,” the Baltimore Sun reports. According to the Sun, “therapies that perform [...]

Several vaccine trials are being postponed or modified following the halt of Merck’s experimental HIV vaccine trial, the Philadelphia Inquirer reports (Stark, Philadelphia Inquirer, 11/16). Merck in September announced that it had ended the Phase II trial, which began in late 2004 and involved HIV-negative volunteers, after the experimental vaccine failed to prevent HIV infection [...]

Previous work has shown that, when a drug study was funded by the company that made that drug, the results might be biased in favour of that drug because the methods or analyses were manipulated.
New research published on bmj.com today shows that, for blood pressure drugs, studies are now much less likely to have biased [...]

Pharmarama.com, a leader in the procurement of pharmaceutical products for comparator trials and named patient programs, announced at BIO-Europe 2007 in Hamburg, Germany, that the firm will be providing complete services to source comparator drugs for clinical trials in China. Pharmarama.com believes that it is the first global clinical trial supply company to have the [...]