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Cytochrome P450 (CYP450) gene testing is currently not recommended to guide treatment with selective serotonin reuptake inhibitor (SSRI) drugs for patients with depression, concludes an expert panel report in the December issue of Genetics in Medicine, published by the American College of Medical Genetics (ACMG) and by Lippincott Williams & Wilkins, a part of Wolters [...]

Researchers at Cedars-Sinai Medical Center’s Department of Psychiatry and Behavioral Neurosciences are seeking participants for a clinical trial examining whether two polyunsaturated Omega-3 fatty acids are effective treatments for depression.
The two fatty acids being studied — docosahexanoic acid (DHA) and eicosapentanoic acid (EPA) — are found naturally in fish oil, flaxseed and walnuts. Previous studies [...]

Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the December 1st issue of Biological Psychiatry explains. This new study reports findings that support the evaluation of a potential new antidepressant agent.
According to the lead [...]

As in most fields of medicine, psychiatry researchers are working to identify specific types of patients, through their individual genetic variations, that may better benefit from particular drugs or combinations of drugs than other patients. A new study, published in Biological Psychiatry’s December 1st issue, investigated whether depressed patients with a particular genetic variation would [...]

Forest Laboratories, Inc. (NYSE: FRX) and H. Lundbeck A/S announced preliminary top-line results from a phase III study of LEXAPRO (escitalopram oxalate) in the treatment of adolescents, aged 12-17, with Major Depressive Disorder (MDD). These results indicate that patients treated with LEXAPRO experienced statistically significant improvement in symptoms of depression, as measured by the study’s [...]

Researchers at the University of Pennsylvania School of Medicine and other study sites have found that transcranial magnetic stimulation (TMS) — a non-invasive technique that excites neurons in the brain via magnetic pulses passed through the scalp — is a safe and effective, non-drug treatment with minimal side effects for patients with major depression who [...]

Bristol-Myers Squibb Company (NYSE: BMY) and Otsuka Pharmaceutical Co., Ltd. announced that the U.S. Food and Drug Administration (FDA) approved the supplemental New Drug Application for ABILIFY(R) (aripiprazole) as adjunctive, or add-on, treatment to antidepressant therapy (ADT) in adults with major depressive disorder (MDD). ABILIFY is the first medication approved by the FDA as add-on [...]

Antidepressants should not be ruled out as treatment for young people with depression, especially since recent studies have shown no connection between these medications and suicide in younger patients, according to an article in the latest Medical Journal of Australia.
Professor Robert Goldney, Professor of Psychiatry at The University of Adelaide, says it is important to [...]

A new report indicates that young adults who have suffered from depression within the past year are at a higher risk of initiating substance use including cigarette smoking and use of alcohol or illicit drugs. The findings, based on the largest national survey on substance use and health, were reported today by the Substance Abuse [...]