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Approximately one in every 500 to 650 baby boys is born with an extra X chromosome, a variation in their genetic code that until a few years ago was thought to result in infertility in all cases. However, this is no longer the case. A recent conference hosted by NewYork-Presbyterian Hospital/Weill Cornell Medical Center and [...]

Approximately one in every 500 to 650 baby boys is born with an extra X chromosome, a variation in their genetic code that until a few years ago was thought to result in infertility in all cases. However, this is no longer the case. A recent conference hosted by NewYork-Presbyterian Hospital/Weill Cornell Medical Center and [...]

A new study of obesity and the probability of pregnancy has shown that a woman’s chances of a spontaneous pregnancy steadily decrease the fatter she is.
In the first prospective cohort study to examine the relationship between body mass index (BMI) and pregnancy chances in women who have no obvious reasons for infertility but who have [...]

Smoking during pregnancy has many adverse effects on fetal development. A new study in mice by Andrea Jurisicova and colleagues at the University of Toronto, Canada, now adds the possibility that smoking before pregnancy or while breast-feeding might substantially decrease the fertility of female offspring to the long list of possible negative outcomes.
The authors found [...]

Mutations in the androgen receptor (AR) gene can cause the androgen insensitivity syndrome (AIS). For complete and severe partial AIS well-characterized in vitro functional assays can be used for genotype-phenotype correlation, however for mild forms of AIS, as associated with male infertility, experimental evidence is scarce or lacking. In particular, optimal in vitro functional tests [...]