MicroRNA-Based Diagnostic Identifies Squamous Lung Cancer With 96 Percent Sensitivity

A new study shows for the first time that a microRNA-based diagnostic test can objectively identify squamous lung cancer with 96% sensitivity, according to Harvey Pass, M.D. of the NYU Cancer Institute at NYU Langone Medical Center, one of the authors of the study published on-line ahead of print in the Journal of Clinical Oncology. […]

DNA Differences May Influence Risk Of Hodgkin Disease

A new analysis has found that certain variations in genes that repair DNA can affect a person’s risk of developing Hodgkin disease. Published in the April 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that differences in these genes should be further investigated to better understand individuals’ […]

Patients’ Fear Should Be Strongly Considered When Counseling Women At High Risk For Breast Cancer

Women at increased risk for breast cancer because of the genetic BRCA mutations are more likely to think a prophylactic mastectomy is the best way to reduce their risk for the disease, compared to other women who are at high risk, according to researchers at The University of Texas M. D. Anderson Cancer Center. The […]

New Therapy Surprisingly Successful For Brain Tumors

The combination of two drugs produces a critical improvement in the treatment of certain brain tumours. This has been demonstrated by researchers at Bonn University working in co-operation with German and Swiss colleagues in a current study. They treated 39 patients who had been diagnosed with a so-called gliablastoma. The patients survived on average 23 […]

Immune Cells From Patients With Rheumatoid Arthritis Have Prematurely Aged Chromosomes

Telomeres, structures that cap the ends of cells’ chromosomes, grow shorter with each round of cell division unless a specialized enzyme replenishes them. Maintaining telomeres is thought to be important for healthy aging and cancer prevention. By this measure, T cells, or white blood cells, from patients with the autoimmune disease rheumatoid arthritis are worn […]

Breast Cancer Research: Safeway Gives $685,000 To TGen

Despite a down economy, Safeway Inc. presented a $685,236 check this week for breast cancer research at the Translational Genomics Research Institute (TGen). Dan Valenzuela, President of Safeway’s Phoenix Division, which includes 116 stores throughout Arizona, thanked the grocery chain’s customers and employees for stepping up for scientific research. “We’re very proud to donate to […]

Newly Discovered Gene Plays Vital Role In Cancer

Gene p53 protects against cancer and is usually described as the most important gene in cancer research. However, scientists at the Swedish medical university Karolinska Institutet have now shown that a previously unknown gene, Wrap53, controls the activity of p53. As the regulation mechanism is relatively unexplored, the study opens up new routes to solving […]

Male Birth Defect May Be Linked To Genetic Mutations

Cryptorchidism, the congenital birth defect in which one or both testicles fail to descend into the scrotum, has been associated with certain genetic mutations, including a syndrome which is also a common cause of infertility, according to a study released on November 19, 2008 in JAMA. As the most common congenital birth defect in male […]

480 Genes That Control Human Cell Division Identified By International Team

A team of U.S., Israeli and German scientists used computational biology techniques to discover 480 genes that play a role in human cell division and to identify more than 100 of those genes that have an abnormal pattern of activation in cancer cells. Malignant cells have lost control of the replication process, so detecting differences […]

Autism And Recurrent Genetic Deletion Linked

Loss of a small portion of chromosome 16, known as 16p11.2, is significantly associated with autism report researchers from the University of Chicago Medical Center, the University of Illinois at Chicago, and the Roswell Park Cancer Institute in a recent article, published online by the journal Human Molecular Genetics. Although this genetic “microdeletion” occurred in […]