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Researchers at the University of California, San Diego School of Medicine have identified a key protein that is required for immune cells called B lymphocytes to divide and replicate themselves. The rapid generation of large numbers of these immune cells is critical to the body’s antibody defense mechanism. However, when B cells grow unchecked, it [...]

Idera Pharmaceuticals, Inc. (Nasdaq: IDRA), a biotechnology company engaged in the discovery and development of DNA- and RNA-based drug candidates targeted to Toll-like Receptors (TLR), today announced the publication of a paper entitled “Treatment of Mammary Carcinomas in HER-2 Transgenic Mice through Combination of Genetic Vaccine and an Agonist of Toll-like Receptor 9″ in Clinical [...]

Telomeres, structures that cap the ends of cells’ chromosomes, grow shorter with each round of cell division unless a specialized enzyme replenishes them. Maintaining telomeres is thought to be important for healthy aging and cancer prevention.
By this measure, T cells, or white blood cells, from patients with the autoimmune disease rheumatoid arthritis are worn out [...]

ImmunoCellular Therapeutics, Ltd. (OTCBB: IMUC) (IMUC), a biotechnology company, today announced that the company has identified new peptide candidates that may significantly expand the potential target patient population for the company’s cancer stem cell vaccine product candidate, ICT-121. Many cancer therapies are limited by their ability to be used only in patients with certain human [...]

The National Institutes of Health’s National Cancer Institute (NCI) has awarded The City College of New York (CCNY) and Memorial Sloan-Kettering Cancer Center (MSKCC) a $15.9 million grant to implement a unique partnership in cancer research, education, and outreach. The five-year, renewable award is funded by NCI’s U54 program, an initiative created to develop partnerships [...]

Women who’ve had a breast biopsy know the anxiety of waiting for the results, but that stress may cause adverse health effects, according to a new study published in the March issue of Radiology.
“When women express how taxing it is to have to wait for results, the medical establishment may dismiss their feelings as psychological,” [...]

University of California, Irvine infectious disease researchers have shown the effectiveness of a potential alternative to the existing smallpox vaccine that can replace the current biodefense stockpile for this lethal virus.
Philip Felgner and Huw Davies with the Department of Medicine found that the modified vaccinia virus Ankara (MVA) produced the same antiviral response in human [...]

A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10).
The discovery fills in an important “missing link” in a biochemical pathway that’s long been tied to disorders ranging from lupus and Type 1 diabetes, [...]

VGX Pharmaceuticals announced today the successful completion of its first study to assess the tolerability of VGX’s patented CELLECTRA™ electroporation device in humans. Ten healthy adult volunteers were treated with CELLECTRA™ device and were asked to report the level of discomfort they experienced immediately after electroporation and at various times thereafter. The procedure was generally [...]

Cornell researchers are using advanced genetic techniques to better understand the relationship between the bacteria that cause tuberculosis and the human immune system defense cells that engulf them.
The researchers have discovered that unlike many bacterial pathogens, Mycobacterium tuberculosis does not react when immune system cells called macrophages initially make contact; but the bacterium’s genes become [...]