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Researchers at Oregon Health & Science University’s Neurological Sciences Institute have uncovered the system that tells the body when to perform one of its most basic defenses against the cold: shivering. The scientists have discovered the brain’s wiring system, which takes temperature information from the skin and determines when a person should start shivering. Their [...]

Intensive rehabilitation training for patients with spinal cord injuries can stimulate new branches growing from severed nerve fibers, alongside compensatory changes in the brain, say Canadian researchers. Most importantly, it could lead to restoring hand function and the ability to walk. A study recently published in the journal Brain highlights the remarkable benefits of rehabilitation [...]

A new study of combat-exposed Vietnam War veterans shows that those with injuries to certain parts of the brain were less likely to develop post-traumatic stress disorder (PTSD). The findings, from the National Institutes of Health (NIH) and the National Naval Medical Center, suggest that drugs or pacemaker-like devices aimed at dampening activity in these [...]

A brain chemical that makes us sleepy also appears to play a central role in the success of deep brain stimulation to ease symptoms in patients with Parkinson’s disease and other brain disorders. The surprising finding is outlined in a paper published online Dec. 23 in Nature Medicine. The work shows that adenosine, a brain [...]

A new potential target in the treatment of a fatal brain disease Hypertensive encephalopathy is an often-fatal disease of the brain that results from extremely high blood pressure. This disorder can lead to a breakdown of the blood-brain barrier (BBB), resulting in fluid accumulation in the brain, a condition known as cerebral edema. The mechanisms [...]

Medtronic, Inc. (NYSE: MDT) announced that the sale of its recently-introduced VERTEX SELECT multi-axial screw is not affected by an injunction issued against the continued sale of the multi-axial screws used in the company’s VERTEX® and VERTEX MAX spinal systems. VERTEX SELECT is an improved, proprietary, multi-axial screw that is a substitute for the enjoined [...]

In conversation, humans recognize words primarily from the sounds they hear. However, scientists have long known that what humans perceive goes beyond the sounds and even the sights of speech. The brain actually constructs its own unique interpretation, factoring in both the sights and sounds of speech. For example, when combining the acoustic patterns of [...]

Investigators at the University of Rochester Medical Center have uncovered a promising drug therapy that offers a ray of hope for children with Batten disease – a rare neurodegenerative disease that strikes seemingly healthy kids, progressively robs them of their abilities to see, reason and move, and ultimately kills them in their young twenties. The [...]

Mitochondrial Calcium Handling at Mossy Fiber Boutons Doyun Lee, Kyu-Hee Lee, Won-Kyung Ho, and Suk-Ho Lee Dentate granule cells essentially can speak with two tongues. The axonal branches of their mossy fibers innervate CA3 pyramidal cells and interneurons, each with distinct morphological and functional properties. Lee et al. stimulated mossy fibers and compared the response [...]

The capacity of the human mind to believe or disbelieve a statement is a powerful force for controlling both behavior and emotion, but the basis of these states in the brain is not yet understood. A new study found that belief, disbelief and uncertainty activate distinct regions of the brain, with belief/disbelief affecting areas associated [...]